Archive for March, 2011

26
Mar

What Is Arthritis Pain?

Posted by Treatment

What is arthritis? The most commonly used definition for arthritis is an inflammation of the joints. The joints of the body are where two bones connect allowing the limbs to bend for movement purposes. Arthritis causes the joints to swell which makes the bones stiff and lessens the flexibility of your movement. It is important to note that arthritis is not a single disease.

There are well over 100 rheumatic diseases that cause pain, swelling and stiffness in the joints that arthritis describes. To make it plain there are many different types of arthritis and many different causes for arthritis. For example osteoarthritis (degeneration of the joints disease)is a form of arthritis and the most common cause of arthritis is hereditary, if a parent suffered from this disease chances are it will get passed on to the children.

Another unavoidable cause of arthritis is old age. It’s no secret that the older a person becomes their chances of them experiencing arthritic pain in their joints increases by a large margin. That’s because the bones of the body begin to degenerate as a person becomes older.

The Number 1 Sign of Arthritis:

The major complaint from people who have a form of arthritis is the joint pain. When the arthritis is in its early stage the pain may come and go but as it grows the pain becomes more constant. The inflammation of the joints is what causes the pain to occur.

Common forms of arthritis:

Arthritis in hands is the most common among people who suffer from severe arthritis pain. Studies have shown that at least 1% of all Americans suffer from arthritis in hands. It is important to note that the first place arthritis attacks are your smaller joints such as arthritis in hands, wrist and feet. As the disease grows it spreads to the larger joints such as, arthritis in knees, elbows, neck and shoulder.

What should I do if I am experiencing arthritis in hands?

The first thing a person who has had or is having symptoms of arthritis should do is set up an appointment with their doctor and get a diagnosis. As we mentioned earlier there are over a 100 arthritic diseases and it’s important to know which one you might have. Understand that just because you have experienced arthritic like symptoms does not mean you have arthritis. The only way to know is to have a diagnosis. So what is arthritis? The best way to define arthritis is to say it is any disease that attacks the joints of the body.

25
Mar

Arthritis Is the Inflammation of One or More Joints

Posted by Treatment

Arthritis is the inflammation of one or more joints. It usually results in pain, swelling, stiffness, and/or limited movement. There are over 100 different types of arthritis. Some of the primary types are osteoarthritis, rheumatoid, septic, gouty, juvenile idiopathic, Still’s disease, and ankylosing spondylitis.

Symptoms
-Some of the symptoms of osteoarthritis
are pain, stiffness, muscle weakness, swelling, deformed joints, reduced range of motion and loss of use of the joint, cracking or creaking.
-Some of the symptoms of rheumatoid arthritis are joint inflammation, fatigue, loss of appetite/weight loss, muscle aches, or malaise/feeling ill.
-Some of the symptoms of septic arthritis are chills, fatigue, fever, inability to move the limb with the infected joint, severe pain in affected joint, swelling, or warmth.
-Some of the symptoms of gout are warmth, pain, swelling, extreme tenderness in a joint. Usually this joint is the big toe. Gouty arthritis can be the most painful type of chronic inflammatory arthritis.
-Children with juvenile idiopathic arthritis may have one or more symptoms such as joint pain, swelling or stiffness, trouble sleeping, or problems walking.
-Some of the symptoms of Still’s disease are a fever, joint paint/warmth/swelling, a pink-colored skin rash, severe muscle aches, or a sore throat.
Some of the symptoms of ankylosing spondylitis are pain and stiffness, bony fusion, or pain in ligaments and tendons.

Causes
Joints are places that two bones rub together.
Cartilage covers the end of each bone to prevent them from moving directly against each other. The joint is nourished by synovial fluid, which surrounds it. Some kinds of arthritis happen when the cartilage wears down, or when there is a lack of fluid.

Treatment
Aquatic therapy is beneficial for people who have with arthritis due to difficulty with weight bearing activities. Blood circulation is increased by the warm temperature of the water that provides heat for the joints. Patients also benefit from the mild resistance provided by the water.

Infrared therapy can effectively help manage arthritis pain since it improves blood circulation and relaxes muscles. The cold laser is effective in helping osteoarthritis and rheumatoid arthritis.

-Although it is viewed officially as investigational, many people suffering from osteoarthritis and rheumatoid arthritis benefit from electrical stimulation. It is used to improve muscle performance, endurance, and maintaining or enhancing muscle strength.

Exercise is an essential part of treating arthritis. Strengthening the surrounding muscles helps to support the joint.

24
Mar

Get Rid of Gout Pain

Posted by Treatment

Those who have had gout will know the terrible pain which accompanies this arthritis attack. Most often, gout patients tend to feel acute pain in their big toe sometime in the middle of the night which leaves them rather alarmed and shaken. Many of such patients are on the lookout for ways and means to get rid of their gout pains forever.

Gout is simply the result of an excessive buildup of uric acid in the body, which accumulated due to various factors, the main one of which happens to be a high purine diet. Uric acid which cannot be eliminated with the help of the kidneys, gradually build up as needle like crystals in the various small joints of the body like the toe, fingers, elbows, knees, etc and cause much pain to the individual concerned.

Gout pains can be rid of using various methods, both natural as well as through prescription drugs. Whatever be your choice, it is important that you prevent successive gout attacks as it can seriously damage your kidneys and joints. A main thing to remember in the treatment of gout is that this disease is actually incurable. You can only manage gout with various remedies so as to prevent frequent attacks and get rid of the pain.

In normal cases, prescription medicines like nsaids, corticosteroids, colchicines, etc used by doctors to manage gout and give relief from pain. The elevated levels of uric acid in the body can also be controlled by the intake of allopurinol too, thereby bringing down the gout pains and recurrent attacks to a great extent. But the problem with such medication is that one needs to take it for a very long period of time, often a lifetime, and once it is stopped, all the symptoms of the disease come up again. Side effects of drugs are also a possibility one can’t ignore and often people who take gout medicines complain of headaches, nausea, vomiting, skin allergy, stomach ache, bleeding, ulcers, etc.

One can also try alternate methods to get rid of gout pains effectively. Natural remedies are very helpful in treating symptoms of gout without any side effects. Some effective natural methods to get rid of gout pain are given below:

Cherries are supposed to be filled with anti inflammatory properties, which makes it an ideal remedy for Gout Pain. Drink Cherry juice or eat about 30 – 40 cherries on a daily basis to get rid of gout pain.
Baking soda has the ability to flush out uric acid from the body. Make a solution of ½ teaspoon baking soda in 8 oz water and drink it 8 – 10 times a day so as to be free from Gout attacks.
Use a hot and cold compress alternatively so as to improve blood circulation on the affected area.

23
Mar

4 Effective Ways to Prevent Formation of Uric Acid Stones

Posted by Treatment

There many types of kidney stones that can form in the kidneys, such as calcium oxalate, calcium phosphate, magnesium ammonium phosphate, etc. For people who are suffering from hyperuricemia or gout, chances are very high that uric acid stones will form at later stages of their life if no measures are taken to lower down the uric acid levels in the body.

Uric acid stones are semi-transparent and hard to be observed under conventional X-Ray diagnosis. You will know you are having it until the stones grow so big that they block some kidney tubules and form bulges that are visible through X-Ray. This means uric acid stone is the most dangerous among all other kidney stones because they may have created many damages to the kidney before you discover it. Thus, it is much better to prevent its formation than to remove it later.

Uric acid stone or precisely known as monosodium urate crystal (MSU) is the result of crystallization of uric acid in the urinary tracts. To prevent its formation is to minimize the conditions that are optimum for crystallization to take place.

1. Reduce the Concentration

Uric Acid has very low solubility. It starts to crystallize when the concentration goes beyond 0.494 millimol/L or 8.3 mg/dL. Thus, to prevent the formation of urate crystals in your kidney, you have to drink at least 2 Litres of water every day to increase the solubility of urine. It is easy to tell if your urine is thick or not. If it is brownish or dark yellowish, it is very concentrated. A healthy person has urine that is slightly yellowish and clear.

2. Increase the pH

It is much easier for uric acid crystals to form under low or acidic pH. Several researches have shown that urate crystals tend to form at the pH below 5.6. Normal urine pH is around 6.5, which is slightly acidic. In order to raise the urine pH back to healthy level, you must include more vegetables and fruits (except berries) in your daily diets. You have to reduce your consumption of high protein foods and minimize your alcoholic drinks.

3. Foot Reflexology

Every organ in our body is connected to certain reflex points in the feet. If possible, go for a professional foot reflexology therapy once a month to stimulate the internal organs, including the kidneys to strengthen their ability to get rid of the acidic toxin out from the body.

4. Sauna or Exercise

Sweat! Go for a jog or sauna at least once a week to have a big sweating session. Skin is the largest organ in the body and there are about 2 million sweat glands all over your body. These are the exit points for your body to get rid of the unwanted acidic wastes too. That is why sweat is salty sour.

If you can discipline yourself to practice at least half of the above mentioned methods, you chance of getting urate stones or gout will be greatly reduced. It is always better to prevent a disease naturally than to depend on those invasive medicines or surgeries to treat it later.

22
Mar

A Brief Introduction To Arthritis Homeopathic Remedies

Posted by Treatment

If you’re suffering from arthritis, one of the ways you can relieve yourself from the pain and stiffness it causes is through the use of arthritis homeopathic remedies. These homeopathic remedies are considered safe to take, very effective, and without the side-effects that most conventional pharmaceuticals may have. This is particularly important when treating arthritis, because any remedy for arthritis should be safe for long-term use.

In fact, this is one of the reasons that people turn to homeopathic remedies: most conventional medicines, as effective as they are, do come with risks for side-effects when used over a long period of time. And, since arthritis is a disease with no known cure, any medication prescribed will be used over a long period of time. To avoid the risks of side-effects, people choose those with no such risks to begin with, like homeopathic remedies.

How do arthritis homeopathic remedies work? First, we have to take a look at how homeopathic medicine treats illness. In the most basic sense, homeopathy works on the belief that “like treats like.” By this they mean that an illness or condition is treatable by using substances that would otherwise cause the same symptoms in a healthy person.

In the case of arthritis, the specific remedies that will be used will typically cause arthritis symptoms in a healthy person. There are, of course, other factors that practitioners of homeopathic medicine consider when they prescribe remedies.

On such consideration is that taking the substances that homeopathic medicine uses could be very harmful. To make sure the substances are safe, they use a process which is called dynamisation or potentisation, wherein the substance is diluted with either alcohol or distilled water that basically makes the substance less harmful. This dilution is then shaken vigorously in a process that homeopathy calls succussion. In this manner, homeopathic dilutions are made effective, and without any harmful side-effects.

The substances alone are not the core of homeopathic medicine, as important as they are to the treatment of an affected individual. Homeopathy also has a focus on proper, complete diagnosis of the individual. By this, they not only determine the illness and its causes, but also any possible emotional factors that could contribute to the sickness. Practitioners of homeopathic medicine often take into consideration much more than those who practice conventional medicine.

For example, the treatment of arthritis may also include the homeopathic practitioner diagnosing that the patient is also suffering from depression, and that the arthritis gets worse during cold, wet days. It could be determined that the arthritis gets worse because of the depression, and that the cold helps cause the depression itself. The prescribed remedy to treat the arthritis will also seek to treat the other ills of the person as well, including the depression, and that he feels worse on certain days, in order to affect a complete treatment of the person.

Arthritis is no doubt a very difficult disease to live with. It can leave you with severe pain and great discomfort. Arthritis homeopathic remedies can be one way to become free of that pain and discomfort, without dependence on conventional drugs and treatments.

20
Mar

Tips For Arthritis Patients

Posted by Treatment

Quite often people in their retirement years will downsize their larger home for a home all on one level. This is a great idea, especially for those who have arthritis. Some people decide to go to an apartment with elevator service; while others move to a warmer climate. Having no stairs to climb, no lawns to mow, no snow removal are all beneficial for arthritis sufferers. Even if you decide to stay in your home there are a host of other things you can do to make your life easier.

In the Kitchen
*Organize your cupboards and storage areas to make sure the things you use most frequently are within easy reach.
*Use a lever for your door handles rather than a knob; they are easier to open and close.
*Use long handles wherever possible; they save you from reaching.
*Use a rubber mat in front of a sink. It is warmer and provides cushioning when standing for long periods.
*Use a kitchen step-stool when you have to reach something out of your normal reach span; or even a high stool to sit on when you have to do longer jobs. It is always easier to sit than to stand.
*There are numerous “gadgets” that you can purchase to help you open lids on tight- fitting jars; electric can
openers for those who have difficulty with hand- held ones.
*You can purchase special handles for your kitchen faucet to make them easier to turn on and off.
*Make the handles on your kitchen pots thicker and easier to handle by wrapping them with foam or bubble wrap.

  • In the Bathroom
    Attach a hand-rail on your bathtub or a “grab bar” inside of the shower which allows easy entry and exit.
  • Having an ample supply of hot water available is important. Arthritis patients find great comfort in soaking
    in a warm bath; which is good for soothing stiff muscles and joints.
  • Having a walk-in shower with a seat and a pulsating shower head is the next best thing to a whirlpool tub.
  • Raise the level of your toilet seat so that it is easier to sit and to stand up.
  • Using an arm-rail on the wall or vanity near the toilet seat is also helpful when trying to stand.
  • Another handy thing to have is an electric or battery operated toothbrush. These really work well for getting
    the teeth clean and are much less work than a regular toothbrush.

 

The Family Room
*It is important to have the room where you spend your leisure time set up so that you are going to be comfortable. Having firm chairs with armrests is not only convenient for getting up from a sitting position; the arms offers support and spreads the load of your body weight more evenly when standing. If the chair is too low, you can raise it by adding a cushion making it easier to push yourself up.
*If you don’t already have one; a good investment is a recliner chair with a footrest. They will reduce the pressure on the hips and knees while sitting. There are chairs on the market today with built-in massage units and vibrators.
*Whatever your choice you will need a chair that is a good fit for your body. If your posture is not good while you are sitting you will surely suffer more pain.

19
Mar

How Exercise Benefits Arthritis Patients

Posted by Treatment

 

Regular exercise benefits everyone by increasing your stamina and energy. If you have arthritis it is especially important to exercise regularly. Not only will you reduce your risk of other diseases; but your joints and muscles will feel better and you will feel more energized.

Arthritis is a common reason for people to give up exercising but inactivity only increases the stiffness and fatigue associated with the disease. Regular exercise will not only improve joint circulation and decrease joint swelling but it also keeps the cartilage and bones healthy.

By understanding physical fitness and exercise you’ll not only feel better; you will improve your health and also manage your arthritis. If you are determined to live a healthier and more productive life and not be at the mercy of arthritis, work out with some of these exercises.

Flexibility Exercises

Flexibility exercises, or range of motion exercises are the foundation of any exercise program. They are especially important for the person with arthritis. The purpose is to increase flexibility in the joints and muscles.

Flexibility exercises should be done slowly and should be performed before more vigorous exercises. Before doing other exercises work up to fifteen minutes with the flexibility exercises so that you will have the endurance needed for strengthening and aerobic exercise.

Strengthening Exercises

Strengthening exercises are also known as resistance exercises. The lack of exercise causes muscles to become weak.

If your muscles are strong, they will be able to absorb shock and support the joints. Having strong muscles is necessary to perform many of our daily tasks. Gradually increase your strengthening exercises so that you are not causing your muscles to become sore after you exercise.

Aerobic Exercises

Aerobic exercises can include walking, hiking, swimming, skating, mowing the lawn, bicycling, playing golf or doing any physical exercise where you are continually moving your legs and arms.

Including aerobics into your fitness program puts you at less risk of developing heart disease, high blood pressure and diabetes. It is the kind of exercise that will help control your weight, strengthen you bones, decreases stress and makes you more energetic. At the same time, it will increase flexibility and improves mobility.

If you are not currently following an exercise program you don’t have to come up with a new exercise to do right away. Just find ways to add more physical activity to your regular daily routines. You could start by taking short ten minute walks three times a day; building your exercise up to thirty minutes. Once you accomplish this; you will be ready to start on other methods of aerobic exercise.

You need to make sure you are exercising on a regular basis and gradually increase the time so that you are not getting exhausted or causing your muscles and joints to become painful by trying to do too much too fast.

When you begin any aerobic exercise it is important that you warm-up. This will raise the temperature in your muscles and joints, increases circulation and flexibility and prepares your heart to work harder. An example of a warm-up routine, if you are walking; would be to walk slowly for ten to fifteen minutes before getting into more vigorous walking.

The cool-down period is important as well. After you have been vigorously walking let your body slow down for the last ten minutes, so that your heart rate slows and you lose some of the heat that you generated by walking vigorously. Slow down to a casual stroll.

Whatever exercise program you decide is best for you, remember to work up to the thirty minutes per day slowly and be consistent for at least three to four days a week.

18
Mar

Rheumatoid Arthritis, Symptoms, Diagnosis and Treatment

Posted by Treatment

Rheumatoid arthritis – a systemic disease of connective tissue, mainly affecting small joints of the type of erosive and destructive polyarthritis of unknown etiology with a complex autoimmune pathogenesis.

Causes of the disease on this day are unknown. Indirect data, such as increasing the number of white blood cell count and erythrocyte sedimentation rate (ESR) indicate the infectious nature of the process. It is believed that the disease develops as a result of infection, which causes a compromised immune system in genetically susceptible individuals, with formation of so-called. immune complexes (of the antibodies, viruses, etc..), which are deposited in tissues and lead to joint damage. But the ineffectiveness of antibiotic treatment of RA is likely to indicate the incorrectness of this assumption.

The disease is characterized by high disability (70%), which comes pretty early. The main causes of death from the disease are infectious complications and renal failure.

Treatment focuses primarily on relieving pain, slowing disease progression and restore damaged by surgery. Early detection of disease with the help of modern tools can significantly reduce the harm that can be inflicted joints and other tissues.

For the first time may occur after heavy physical exertion, emotional shock, fatigue, hormonal changes during the period, the impact of adverse factors or infection.

Epidemiology

Rheumatoid arthritis is distributed worldwide and it affects all ethnic groups. Prevalence of 0,5-1% (up 5% in the elderly) ratio M: F = 1:3 peak of illness onset – 30-35 years

Etiology

As with most autoimmune diseases, there are 3 main factors:

1. Hereditary susceptibility to autoimmunity.

2. Infection factor Hypothetical triggers of rheumatic diseases

Paramyxovirus – viruses, mumps, measles, respiratory syncytial infection

Hepatitis B virus

Herpes virus – herpes simplex viruses, herpes zoster, cytomegalovirus, Epstein-Barr virus (much higher in the synovial fluid of RA patients

Retroviruses – T-lymphotropic virus

3. Start-up factor (hypothermia, insolation, intoxication, mutagenic drugs, endocrinopathy, stress, etc.). For women, duration of breast-feeding reduces the risk of RA. Breastfeeding for 24 months or more reduces the risk of developing RA by half.

The course of disease

Rheumatoid arthritis progresses in three stages. In the first stage, the swelling of the synovial bags causing pain, heat and swelling around the joints. The second stage is the rapid cell division that leads to compaction of the synovial membrane. In the third stage, the inflamed cells release an enzyme that attacks the bones and cartilage, which often leads to deformation of the affected joints, increasing pain and loss of motor functions.

Typically, the disease progresses slowly at first, with the gradual deployment of clinical symptoms for several months or years, much less – subacute or acute. In about 2 / 3 of cases fever occurs, and the rest – a mono-or oligoarticular form, and articular syndrome often has no clinical specificity, which greatly complicates the differential diagnosis. Articular syndrome is characterized by morning stiffness for more than 30 minutes and similar expressions in the second half of the night – symptoms of “stiff gloves”, “corset”; ongoing spontaneous pain in the joints, increasing during active movements. The disappearance of the stiffness depends on the activity of the process: the more activity, the greater the duration of restraint. For the joint syndrome in rheumatoid arthritis is characterized by monotony, the duration, preservation of residual effects after treatment.

There may be prodromal clinical symptoms (mild transient pain, pain relationship with meteorological conditions, autonomic dysfunction). Distinguish “joint damage” and “joints exception.” Rheumatoid arthritis is often combined with other joint diseases – osteoarthritis, rheumatism, systemic connective tissue diseases.

Allocate the following options for the clinical course of rheumatoid arthritis:

The classic version of the (symmetric defeat both small and large joints

Mono-or oligoarthritis, mainly affecting the large joints, most often the knee. Severe disease onset and reversibility of all manifestations during 1-1,5 months (arthralgias are migratory in nature, radiographic changes are absent, anti-inflammatory drugs offer relatively positive effect in the latter there are all the symptoms of rheumatoid arthritis).

Diagnosis

Diagnosis of rheumatoid arthritis (RA) – For a long time there was no specific test that would unambiguously confirm the presence of the disease. Currently, diagnosis of disease based on biochemical analysis of blood, changes in the joints are visible on x-rays, and the use of basic clinical markers, but also in conjunction with the general clinical manifestations – fever, malaise, and weight loss

In the analysis of blood examined ESR, rheumatoid factor, platelet count, etc. The most advanced analysis is the titer of antibodies to cyclic citrulline-containing peptides – ACCP, anti-CCP, anti-CCP. The specificity of this indicator is 90%, while it is present in 79% of sera from patients with RA.

Diagnostically important clinical features are the lack of discoloration of the skin over the inflamed joints, the development of tenosynovitis flexors or extensors of the fingers and the formation of amyotrophy, typical strains of brushes, so-called “rheumatoid wrist.

The criteria for poor prognosis are:

1. Early damage of large joints and the appearance of rheumatoid nodules
2. swollen lymph nodes
3. involvement of new joints in the subsequent exacerbation;
4. systemic disease;
5. persistent disease activity with no remission for over a year;
6. persistent increase in the ESR;
7. early appearance (within the first year) and high titers of rheumatoid factor
8. early (up to four months), radiographic changes in the affected joints – a rapid progression of destructive changes;
9. Detection of antinuclear antibodies and LE-cells
10. Carrier antigens HLA-DR4

Symptoms

Rheumatoid arthritis can begin at any joint, but most often starts from small joints in the fingers, hands and wrists. Typically, joint damage is symmetric, for example if the sore joint on his right hand, then ill be the same joint on the left. The more joints afflicted the more advanced stages of disease.

Other common symptoms include:

Fatigue
Morning stiffness. Generally, the longer the constraint, the disease activity.
Weakness
Flu-like symptoms, including low heat.
Pain during prolonged sitting
Outbreaks of disease activity are accompanied by remission.
Muscle pain
Loss of appetite, depression, weight loss, anemia, cold and / or sweaty palms and feet
Violation of glands near the eyes and mouth, causing insufficient production of tears and saliva.

Treatment

In the presence of infection need the appropriate antibacterial therapy. In the absence of bright extra-articular manifestations (eg, high fevers, Felty’s syndrome or polynervopathy) treatment of joint syndrome begin with the selection of non-steroidal anti-inflammatory drugs (NSAIDs). At the same time in the most inflamed joints injected corticosteroids. An important point in the treatment of rheumatoid arthritis is the prevention of osteoporosis – restoration of the calcium balance in the direction of increasing its absorption in the intestine and reduced the excretion. Sources of calcium are dairy products (especially cheese, which contains from 600 to 1000 mg of calcium per 100 g of the product, as well as cheese, to a lesser degree of cottage cheese, milk, sour cream), almonds, hazelnuts and walnuts, etc., and calcium supplements in combination with vitamin D or its active metabolite.

Importance in the treatment is therapeutic exercise, aimed at maintaining maximum joint mobility and maintaining muscle mass.

Physiotherapy (electrophoresis of nonsteroidal anti-inflammatory drugs, hydrocortisone phonophoresis) and spa treatment. With persistent mono-and oligoarthritis includes introduction of isotopes of gold, yttrium, etc., With persistent strains of joints is carried out reconstructive surgery.

Modern Therapy

Systemic drug therapy involves the use of four classes of drugs:

1. nonsteroidal anti-inflammatory drugs (NSAIDs),
2. basic drugs
3. glucocorticosteroids (GCS)
4. biological agents.

Non-steroidal anti-inflammatory drugs
NSAIDs remain the first line of therapeutic agents that are directed primarily to the relief of acute manifestations of the disease, as well as ensuring stable clinical and laboratory remission.

In the acute phase of illness use of NSAIDs, corticosteroids, pulse therapy with corticosteroids or in combination with cytotoxic immunosuppressive agents.

Current NSAIDs have a marked anti-inflammatory effect which is caused by inhibition of the activity of cyclooxygenase (COX) – a key enzyme of arachidonic acid metabolism. Of particular interest is the discovery of two isoforms of COX, which are identified as COX-1 and COX-2 and play different roles in regulating the synthesis of prostaglandins (PG). Proved that NSAIDs inhibit the activity of COX isoforms, but their anti-inflammatory activity is due to inhibition of COX-2.

Most of the known NSAIDs inhibit primarily COX-1 activity, which explains the appearance of complications such as gastropathy, renal failure, encephalopathy, hepatotoxicity.

Thus, depending on the nature of blocking COX, NSAIDs are divided into selective and nonselective COX-2 inhibitors.

Representatives of the selective COX-2 inhibitors are meloxicam, nimesulide, celecoxib. These drugs have minimal side effects and retain high anti-inflammatory and analgesic activity. COX-2 inhibitors can be used in all programs of the treatment of rheumatoid arthritis, which require the use of NSAIDs. Meloxicam (Movalis) in the early treatment of inflammatory activity assigned to 15 mg / day and subsequently transferred to 7.5 mg / day as maintenance therapy. Nimesulide is assigned a dose of 100 mg twice a day.

Celecoxib (Celebrex) – a specific inhibitor of COX-2 – is assigned to 100-200 mg twice a day. Selection for the elderly dosage of the drug is not required. However, patients with body weight below the median (50 kg) it is desirable to begin treatment with the lowest recommended dose.

You should avoid combining two or more NSAIDs, because of their effectiveness remain unchanged, and the risk of side effects increases.

Basic Preparations

Basic drugs continue to play a pivotal role in the treatment of rheumatoid arthritis, but now there has been a new approach to their destination. In contrast to the well-known tactic of gradual treatment of rheumatoid arthritis (“principle of the pyramid”), is now advocated early aggressive treatment of basic drugs immediately after diagnosis, the purpose of which – changed the flow of rheumatoid arthritis and remission maintenance. The reason for this are the lack of early rheumatoid arthritis deformities, osteopenia, and severe complications, formed by autoimmune mechanisms, the high likelihood of remission.

The main drugs of basic therapy of rheumatoid arthritis include: methotrexate, sulfasalazine, gold preparations, D-penicillamine,. By means of the reserve include cyclophosphamide, azathioprine, cyclosporine A. The new group consisted of the following drugs: Remicade.

Ineffective for 1.5-3 months of basic drugs should be replaced or used in combination with corticosteroids in low doses, thus reducing the activity of rheumatoid arthritis before the start of the first. Six months – a critical period, no later than that should be adjusted effective basic therapy.

The best preparation for the start of basic therapy in severe rheumatoid arthritis and RF-positivity, presence of extraarticular manifestations of methotrexate is considered – cytotoxic immunosuppressive agent, which is well tolerated for prolonged use and has fewer side effects than other drugs of this group.

In the treatment of basic drugs carefully monitored the activity of the disease and side effects.

Corticosteroids

A new approach is the use of high doses of corticosteroids (pulse therapy) in combination with slow acting tools that can improve the efficiency of the latter; combinations of methotrexate with salts of gold, sulfasalazine, as well as a selective immunosuppressive agent cyclosporin A.

With a high degree of inflammatory activity are used corticosteroids, and in cases of systemic manifestations of rheumatoid arthritis a form of pulse therapy is used. Corticosteroids only or in combination with cytostatic drugs – cyclophosphamide. SCS is also used as supporting anti-inflammatory therapy after failure of other medicines.

In some cases, corticosteroids are used as local therapy. The indications for their use are: mostly mono-or oligoarthritis of large joints,

Biological agents

In rheumatoid arthritis the synovial membrane, for unclear reasons, secrete a large amount of the enzyme glucose-6-phosphate dehydrogenase that also destroys the disulfide bonds in the cell membrane. In this case, there is “leakage” of proteolytic enzymes from the cell lysosomes, which cause damage to surrounding bones and cartilage. The body responds to this by making cytokines, among which also has a tumor necrosis factor -the A TNF. Cascade of these reactions in cells are triggered by cytokines, further aggravating the symptoms of the disease. Chronic rheumatoid inflammation associated with TNF-α, often causing damage to the cartilage and joints, leading to physical disability.

The treatment uses a monoclonal antibody to the cytokine TNF-the A, which is effective with high affinity in binding to TNF, both in its soluble and transmembrane forms resulting in neutralizing activity of TNF.

During the progression of rheumatoid arthritis, Joint damage in patients with rheumatoid arthritis is observed as a narrowing of the joint space between bones and erosion of bone in the articular space. Clinical trials of monoclonal antibody showed its use as a slow erosion and narrowing of the space between the bones.

16
Mar

How And Why Arthritis Patients Should Walk To Maintain Mobility

Posted by Treatment

Walking can relieve stress, strengthen your bones and muscles, controls weight and makes your body feel good. Walking is an inexpensive aerobic exercise that almost anybody can participate in even if you have arthritis. Keeping active with exercise is one of the best things you could do if you have arthritis. Check out good walking trails in your area; or if you have paved sidewalks. Walking in the winter could present problems especially if you are in an area where there is snow and the sidewalks are not cleared. Another alternative would be to walk in the local malls.

Most people who have arthritis are capable of walking for exercise. If you can walk when you shop, or do household chores then you can walk for exercise. You should be careful when first starting to walk; doing only about ten minutes each time for the first two weeks. You should gradually build up your walking routine by a few minutes each week until you reach thirty minutes. Choose where you walk very carefully and make sure you have a good level surface. It is likely you will find good walking areas in malls, designated walking trails, and on paved sidewalks. You should stay away from hills, soft ground or gravel as these surfaces can be difficult to walk on and could lead to knee, hip, or foot pain. If you walk slowly for about five minutes this will warm your muscles up and gets you ready for a brisk walk. This is called the warm-up. When you are finishing your walk you need to do the cool-down. That means for the last five minutes of your walk, you’ll just stroll. This allows your body to cool slowly after building up heat from walking vigorously.

When you start walking as an aerobic exercise it takes practice to find the right speed for you. Remember to start of with a stroll, then gradually increase your speed until you feel comfortable. If you find that you can’t walk fast enough to increase your heart rate; then try bending your arms at the elbows while carrying a one or two- pound weight and swinging your arms vigorously. The extra work you are doing with your arms increases your heart rate without forcing you to walk faster than you find comfortable.

If you notice any discomfort with knee pain after you have been walking try knee flexibility exercises before and after you walk. Then you could add some strengthening exercises. This should reduce any pain you may be getting after walking.

Comfortable shoes for walking is something you will want to consider. It might be wise to invest in a good pair of running shoes with shock-absorbing soles and insoles. There are tons of different styles to choose from in the marketplace today and at reasonable prices. Make sure your shoes fit properly and don’t slip up and down on your heels while walking. Velcro closures are great for people with arthritis in the fingers and require no effort to close.

Remember, shedding extra pounds by exercising is not only good for your heart it also lessens the pressure on the joints. People who exercise on a regular basis look better, feel better, sleep better and have more energy.

15
Mar

What to Eat for a Gout Relief Diet

Posted by Treatment

Have you ever wondered what foods are best to eat for a gout relief diet? You aren’t alone. Every day people are diagnosed with gout and wonder: what foods should I start including in my diet to help ease my symptoms and make my life easier? The good news is that eating a gout-friendly diet isn’t difficult and it can even be delicious. Think it’s too good to be true? Read on right now to learn a whole lot more.

When it comes to getting relief from your gout you want to make sure you realize the overall importance of the changes. You need to change your lifestyle and mindset, not just your diet. For example including a few foods in your diet won’t change your symptoms or your problems automatically it is merely a piece of a much larger puzzle. As far as what to eat for a gout relief diet you will want to include:

  • Plenty of water throughout the day (2 to 4 liters) and especially on days when you’re active.
  • Less sodas and sugary drinks including juices with added sugars.
  • More fresh fruits like cherries, pineapples, apples, strawberries and grapes.
  • Less foods like anchovies, beef and liver.
  • Your best bet for actually getting your gout cured is through trying to be more active and staying hydrated while controlling your diet. Since gout is caused by uric acid crystallizing around your joints you want to do your best to keep your body flushing out toxins and staying at peak performance. This means exercising at an appropriate level suitable to your capabilities and drinking plenty of water.

    For the most part what to eat for a gout relief diet will include fresh and natural foods in your diet mostly like greens and fruits. Many different meats cause your uric acid levels to spike when they’re being digested in the body and this causes your gout symptoms to flare up. As a result you will want to make sure you avoid certain animal products so you can better control your gout flare-ups. If you’re physically capable to do exercise then going for brisk walks and staying mobile can help your circulation and mobility thus reducing the symptoms of your gout attacks.

    Overall treating the problem boils down to an overall change in lifestyle. You will want to eat differently, be more active and pay more attention to the foods and drinks you ingest. With proper care and attention you can easily eliminate your symptoms altogether if not drastically reduce them.